AMAP Assessment 2009: Human Health in the Arctic

Publisher: Arctic Monitoring and Assessment Programme (AMAP), Publication date: 2009 , Published in series: AMAP Assessments

A comparison of lipid results for two laboratories

A comparison of lipid results for two laboratories
A comparison of lipid results for two laboratories

Administrative areas of the northern Russian Federation

Administrative areas of the northern Russian Federation
Administrative areas of the northern Russian Federation

Age-gender population structure of Arctic countries and regions

Age-gender population structure of Arctic countries and regions
Age-gender population structure of Arctic countries and regions

Age-gender population structure of Russia and Canada in comparison to their Arctic regions

Age-gender population structure of Russia and Canada in comparison to their Arctic regions
Age-gender population structure of Russia and Canada in comparison to their Arctic regions

Age-gender population structure of Sweden and Finland in comparison to their Arctic regions

Age-gender population structure of Sweden and Finland in comparison to their Arctic regions
Age-gender population structure of Sweden and Finland in comparison to their Arctic regions

An individual participant’s performance using RSZs

An individual participant’s performance using RSZs
An individual participant’s performance using RSZs

Annual consumption of traditional food in and Kanchalan

Annual consumption of traditional food in (a) Uelen (coastal Chukchi and Inuit) and (b) Kanchalan (inland Chukchi), on the Chukotka Peninsula, north-east Russia
Annual consumption of traditional food in and Kanchalan

Calculation of total lipids in serum from enzymatic data

Calculation of total lipids in serum from enzymatic data
Calculation of total lipids in serum from enzymatic data

Circumpolar age-standardized mortality rates by cause per 100 000 persons

Circumpolar age-standardized mortality rates by cause per 100 000 persons; standardized to European Standard Population
Circumpolar age-standardized mortality rates by cause per 100 000 persons

Common causes of death in some Arctic populations, 2000 – 2004

Common causes of death in some Arctic populations, 2000 – 2004
Common causes of death in some Arctic populations, 2000 – 2004

Comparison of concentrations of sum of PBDEs in two Quebec populations

Comparison of concentrations of sum of PBDEs in two Quebec populations
Comparison of concentrations of sum of PBDEs in two Quebec populations

Comparison of precision and accuracy

Comparison of precision and accuracy
Comparison of precision and accuracy

Comparison of total lipid results obtained from gravimetric and enzymatic methods

Comparison of total lipid results obtained from gravimetric and enzymatic methods
Comparison of total lipid results obtained from gravimetric and enzymatic methods

Daily intake of POPs in 90 daily food portions as a function of seafood types present in the diet

Daily intake of POPs in 90 daily food portions as a function of seafood types present in the diet
Daily intake of POPs in 90 daily food portions as a function of seafood types present in the diet

DDE concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

DDE (p,p’-DDE) concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
DDE concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

DDE concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

DDE (p,p’-DDE) concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
DDE concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

DDE concentrations in breast milk from various regions of Finland and northern Russia

DDE concentrations in breast milk from various regions of Finland and northern Russia
DDE concentrations in breast milk from various regions of Finland and northern Russia

Definitions of the Arctic region

Definitions of the Arctic region
Definitions of the Arctic region

Different types of biomarker in the pathogenic sequence between exposure and disease

Different types of biomarker in the pathogenic sequence between exposure and disease
Different types of biomarker in the pathogenic sequence between exposure and disease

Effect of mercury and dioxin-like compounds on the pathogenesis of diabetes and its complications

Effect of mercury and dioxin-like compounds on the pathogenesis of diabetes and its complications
Effect of mercury and dioxin-like compounds on the pathogenesis of diabetes and its complications

Effects of PPAR- α, PPAR-β/δ, and PPAR-γ in various tissues

Effects of PPAR- α, PPAR-β/δ, and PPAR-γ in various tissues
Effects of PPAR- α, PPAR-β/δ, and PPAR-γ in various tissues

Exceedance of blood guideline values for mercury and lead in mothers and women of child-bearing age (a)

Exceedance of blood guideline values for (total) mercury and lead in mothers and women of child-bearing age in different populations around the Arctic (comparable data were not available from Norway, [..]
Exceedance of blood guideline values for mercury and lead in mothers and women of child-bearing age (a)

Exceedance of blood guideline values for mercury and lead in mothers and women of child-bearing age (b)

Exceedance of blood guideline values for (total) mercury and lead in mothers and women of child-bearing age in different populations around the Arctic (comparable data were not available from Norway, [..]
Exceedance of blood guideline values for mercury and lead in mothers and women of child-bearing age (b)

Exceedance of blood guideline values for PCB in mothers and women of child-bearing age in different populations around the Arctic

Exceedance of blood guideline values for PCB (measured as Aroclor) in mothers and women of child-bearing age in different populations around the Arctic (comparable data were not available from Norway, [..]
Exceedance of blood guideline values for PCB in mothers and women of child-bearing age in different populations around the Arctic

Genes, macronutrients, and contaminants may have synergistic effects on the development of diseases

Genes, macronutrients, and contaminants may have synergistic effects on the development of diseases. The probability for illness is increased when several pre-disposing factors are simultaneously [..]
Genes, macronutrients, and contaminants may have synergistic effects on the development of diseases

Genetic and environmental factors increase in concert the susceptibility of an individual for public health problems such as, type II diabetes and metabolic syndrome

Genetic and environmental factors increase in concert the susceptibility of an individual for public health problems such as, type II diabetes and metabolic syndrome. All these conditions may have [..]
Genetic and environmental factors increase in concert the susceptibility of an individual for public health problems such as, type II diabetes and metabolic syndrome

Genetic variability in susceptibility to toxicants

Genetic variability in susceptibility to toxicants
Genetic variability in susceptibility to toxicants

Individual PCB congener performance over time

Individual PCB congener performance over time.
Individual PCB congener performance over time

Infant mortality components in Nunavut 1999 – 2004

Infant mortality components in Nunavut 1999 – 2004
Infant mortality components in Nunavut 1999 – 2004

Interactions between the uric acid formation pathway and dietary and environmental factors

Interactions between the uric acid formation pathway and dietary and environmental factors
Interactions between the uric acid formation pathway and dietary and environmental factors

Lipid analysis performance over time

Lipid analysis performance over time. Data from all participants are plotted
Lipid analysis performance over time

Local food percentage, contaminant and nutrient content measured in duplicate meal portions from Greenland

Local food percentage, contaminant and nutrient content measured in duplicate meal portions from Uummannaq, Greenland in 1976 and 2004 and Narsaq, Greenland in 2006
Local food percentage, contaminant and nutrient content measured in duplicate meal portions from Greenland

Location of Arctic indigenous peoples

Location of Arctic indigenous peoples
Location of Arctic indigenous peoples

Locations and ethnicity of populations included in AMAP human health studies

Locations and ethnicity of populations included in AMAP human health studies
Locations and ethnicity of populations included in AMAP human health studies

Locations and ethnicity of populations included in AMAP human health studies

Locations and ethnicity of populations included in AMAP human health studies
Locations and ethnicity of populations included in AMAP human health studies

Metabolism of polyunsaturated fatty acids

Metabolism of polyunsaturated fatty acids
Metabolism of polyunsaturated fatty acids

North American circumpolar region showing schematically possible source and migration routes

North American circumpolar region showing schematically possible source and migration routes of three Arctic cultures and frequency of mtDNA subcluster in Arctic and North American populations.
North American circumpolar region showing schematically possible source and migration routes

Oxychlordane concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Oxychlordane concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
Oxychlordane concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Oxychlordane concentrations in breast milk from various regions of Finland and northern Russia

Oxychlordane concentrations in breast milk from various regions of Finland and northern Russia
Oxychlordane concentrations in breast milk from various regions of Finland and northern Russia

PBDE concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

PBDE (sum of BDE47, BDE99, BDE100 and BDE153) concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
PBDE concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

PCB (CB153) concentrations in breast milk from various regions of Finland and northern Russia

PCB (CB153) concentrations in breast milk from various regions of Finland and northern Russia
PCB (CB153) concentrations in breast milk from various regions of Finland and northern Russia

PCB concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

PCB (CB153) concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
PCB concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Performance trends for individual analytes: CB138

Performance trends for individual analytes: CB138. Data from all participants are plotted
Performance trends for individual analytes: CB138

Performance trends for individual analytes: CB28

Performance trends for individual analytes: CB28. Data from all participants are plotted
Performance trends for individual analytes: CB28

Performance trends for POPs 2002 to 2006

Performance trends for POPs 2002 to 2006
Performance trends for POPs 2002 to 2006

PFOS concentrations in blood of mothers,pregnant women and women of child-bearing age in the circumpolar countries

PFOS concentrations in blood of mothers,pregnant women and women of child-bearing age in the circumpolar countries
PFOS concentrations in blood of mothers,pregnant women and women of child-bearing age in the circumpolar countries

POPs related xenobiotic serum activities in Inuit and combined European study groups (a)

POPs related xenobiotic serum activities in Inuit and combined European study groups (a) agonistic serum xenoestrogenic activity. * indicates significant difference vs Europeans at p < 0.05.
POPs related xenobiotic serum activities in Inuit and combined European study groups (a)

POPs related xenobiotic serum activities in Inuit and combined European study groups (b)

POPs related xenobiotic serum activities in Inuit and combined European study groups (b) agonistic serum xenoandrogenic activity. * indicates significant difference vs Europeans at p < 0.05.
POPs related xenobiotic serum activities in Inuit and combined European study groups (b)

POPs related xenobiotic serum activities in Inuit and combined European study groups (c)

POPs related xenobiotic serum activities in Inuit and combined European study groups (c) serum AhR activity. * indicates significant difference vs Europeans at p < 0.05.
POPs related xenobiotic serum activities in Inuit and combined European study groups (c)

POPs related xenobiotic serum activities in Inuit and combined European study groups (d)

POPs related xenobiotic serum activities in Inuit and combined European study groups (d) sperm DNA damage. * indicates significant difference vs Europeans at p < 0.05.
POPs related xenobiotic serum activities in Inuit and combined European study groups (d)

POPs related xenobiotic serum activities in Inuit and combined European study groups (e)

POPs related xenobiotic serum activities in Inuit and combined European study groups (e) sperm DNA fragmentation index. * indicates significant difference vs Europeans at p < 0.05.
POPs related xenobiotic serum activities in Inuit and combined European study groups (e)

Potential methods for improving public health

Potential methods for improving public health
Potential methods for improving public health

Relationship between genetic diversity and population numbers

Relationship between genetic diversity and population numbers
Relationship between genetic diversity and population numbers

Representative comet images for a healthy donor, benzo[a]pyrene diol epoxide treated cells from a healthy donor, a participant with low DNA damage and a participant with some DNA damage

Representative comet images for (a) a healthy donor (%DNA in tail = 0.67); (b) benzo[a]pyrene diol epoxide treated cells from a healthy donor (%DNA in tail = 32.9); (c) a participant with low DNA [..]
Representative comet images for a healthy donor, benzo[a]pyrene diol epoxide treated cells from a healthy donor, a participant with low DNA damage and a participant with some DNA damage

Schematic illustration of the pathways of steroid hormone biosynthesis

Schematic illustration of the pathways of steroid hormone biosynthesis
Schematic illustration of the pathways of steroid hormone biosynthesis

Self-reported level of traditional food consumption

Self-reported level of traditional food consumption (low, medium, and high). Comparison between baseline (1998/1999) and MOMs study (2005/2006)
Self-reported level of traditional food consumption

Temporal trends of POPs and metals in maternal blood samples from Nunavik, Canada

Temporal trends of POPs and metals in maternal blood samples from Nunavik, Canada
Temporal trends of POPs and metals in maternal blood samples from Nunavik, Canada

Temporal trends of POPs and metals in maternal blood samples from Nuuk and Disko Bay, Greenland

Temporal trends of POPs and metals in maternal blood samples from Nuuk and Disko Bay, Greenland
Temporal trends of POPs and metals in maternal blood samples from Nuuk and Disko Bay, Greenland

The paradigm of interactions between genes and environment and development of a clinical phenotype

The paradigm of interactions between genes and environment and development of a clinical phenotype
The paradigm of interactions between genes and environment and development of a clinical phenotype

The various elements of the risk assessment process

The various elements of the risk assessment process
The various elements of the risk assessment process

Total mercury concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Total mercury concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
Total mercury concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Toxaphene concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Toxaphene (parlar-50) concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries
Toxaphene concentrations in blood of mothers, pregnant women and women of child-bearing age in the circumpolar countries

Trend in participation in the AMAP Ring-tests

Trend in participation in the AMAP Ring-tests
Trend in participation in the AMAP Ring-tests

Trends in infant mortality rate among Inuit in different circumpolar regions in comparison with the general population of the respective countries

Trends in infant mortality rate among Inuit in different circumpolar regions in comparison with the general population of the respective countries.
Trends in infant mortality rate among Inuit in different circumpolar regions in comparison with the general population of the respective countries